STAPHYLOCOCCAL COMPLEMENT EVASION PROTEIN SBI STABILISES C3D DIMERS BY INDUCING AN N-TERMINAL HELIX SWAP

Staphylococcus aureus is an opportunistic pathogen that is able to thwart an effective host immune response by producing a range of immune evasion molecules, including S.aureus binder of IgG (Sbi) which interacts directly with the central complement component C3, its fragments and associated regulators.Recently we reported the first structure of Wi